He is a sculptor, painter, graphic artist and a witty colourist. Kofi Setordji fabricates and optimizes his own tools. He does a lot with lines "vertical and horizontal - to create forms
His designs tend to be somewhat raw, indicative of nature. Even though he considers himself first a sculptor, his contemporary paintings of African women reflect a totally different style. His acrylic works on canvas tend to be more whimsical and more full-bodied than the sculptures, almost Picasso-like in structure.
He has participated in a series of solo and collective exhibitions in Ghana and abroad including USA, Great Britain, Germany and Belgium as well as in numerous African countries. He collaborated with Nat Nunoo-Amarteifio in an exhibition at Nubuke Foundation dubbed "Architectural Heritage of Accra" between 21st and 28th June, 2009. The purpose was to document images of such buildings before they were demolished to make way for new ones in Accra.
In 1990, he was presented the award of Artist of the Year. Amongst his major works there are two large bas-reliefs, one at the Kotoka International Airport of Accra and the other at the Kwame Nkrumah Mausoleum.
He is one of the founding members of Workshop 358 Artists Collective based in Accra.